AURKA-IN-4 [CAS 89575-11-1]

AURKA-IN-4 (compound 13), a capsaicin-derived prohibitin ligand, is an AURKA inhibitor. AURKA-IN-4 acts as a molecular glue within the AURKA/PHB2/LC3 complex. AURKA-IN-4 is specific to the mitochondrial pool of AURKA, and inhibits AURKA-dependent mitophagy. AURKA-IN-4 can be used for cancer research[1].

[89575-11-1]

C12H17NO3

223.27

COC1=CC(CNC(CCC)=O)=CC=C1O

Aurora Kinase; Mitochondrial Metabolism; Molecular Glues

Room temperature