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Aurora A/PKC-IN-1 [CAS 3031505-76-4]
Aurora A/PKC-IN-1 [CAS 3031505-76-4]
SKU:QM-0065791
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Product Details
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Description
Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, and θ) kinases with IC50s of 6.9 nM and 16.9 nM for AurA and PKCα, respectively. Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells and antimetastatic activity[1].
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CAS Number
[3031505-76-4]
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Molecular Formula
C16H14N6OSe2
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Molecular Weight
464.24
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Smiles
O=C1N(C2=NC(N[C@@H]3C[Se]CC3)=C4N=CNC4=N2)[Se]C5=C1C=CC=C5
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Target
Aurora Kinase; PKC
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Isoform
Aurora A; PKCα
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Aurora A/PKC-IN-1 [CAS 3031505-76-4]
Aurora A/PKC-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.