AV-412 (free base) [CAS 451492-95-8]

Name: AV-412 (free base) [CAS 451492-95-8]
Brand: QuantiMol
SKU: QM-0083326-01
Price: 186.08 GBP
Availability: InStock

Size 5 mg 10 mM - 1 mL 10 mg 50 mg 100 mg

SKU:QM-0083326-01

£186.08 GBP

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Product Details

Description
AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.
CAS Number
[451492-95-8]
Molecular Formula
C27H28ClFN6O
Molecular Weight
507
Smiles
O=C(C=C)NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1C#CC(C)(C)N(CC4)CCN4C
Target
EGFR
Isoform
EGFR/ErbB1/HER1; ErbB2/HER2
Purity
98.33
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302-H315-H319-H335
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0083326-01	5 mgQM-0083326-01 £186.08/ea	£0.00	Quantity	£186.08/ea	£0.00

10 mM - 1 mLQM-0083326-02	10 mM - 1 mLQM-0083326-02 £200.66/ea	£0.00	Quantity	£200.66/ea	£0.00

10 mgQM-0083326-03	10 mgQM-0083326-03 £275.99/ea	£0.00	Quantity	£275.99/ea	£0.00

50 mgQM-0083326-04	50 mgQM-0083326-04 £727.97/ea	£0.00	Quantity	£727.97/ea	£0.00

100 mgQM-0083326-05	100 mgQM-0083326-05 £1,029.29/ea	£0.00	Quantity	£1,029.29/ea	£0.00

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AV-412 (free base) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.