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SKU:QM-0105364-01
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AWD 12-281 is an orally active and highly selective phosphodiesterase 4 (PDE4) inhibitor (IC50 = 9.7 nM) . AWD 12-281 is used in the study of allergic dermatitis, asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis[1][2].
[257892-33-4]
C22H14Cl2FN3O3
458.27
O=C(C(C1=CN(CC2=CC=C(C=C2)F)C3=C1C=C(O)C=C3)=O)NC4=C(Cl)C=NC=C4Cl
Phosphodiesterase (PDE)
PDE4
Room temperature
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AWD 12-281 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.