Axelopran [CAS 949904-48-7]

Axelopran (TD-1211) is an opioid receptor antagonist with pKi values of 9.8, 8.8 and 9.9 for human recombinant μ and δ receptors and guinea pig κ receptor, respectively.

[949904-48-7]

C26H39N3O4

457.61

O=C([C@@H](O)CO)N(CC1CCCCC1)CCN2[C@H]3C[C@H](C4=CC(C(N)=O)=CC=C4)C[C@@H]2CC3

Opioid Receptor

δ Opioid Receptor/DOR; κ Opioid Receptor/KOR; μ Opioid Receptor/MOR

Room temperature

H302

P264-P270-P330-P501