Axl-IN-19 [CAS 2870696-46-9]

Axl-IN-19 (Compound 68) is a selective AXL (a membrane-bound receptor tyrosine kinase) inhibitor (IC50: 5.3 nM; Cellular KD = 6.8 nM) . Axl-IN-19 has favorable rat PK with low clearance and moderate bioavailability. Axl-IN-19 can be used for cancer research[1].

[2870696-46-9]

C31H33N5O2

507.63

CN(C(C1=CC=C(C=C1)C2=NNC3=NC=C(C=C32)C4=CC=C5CC[C@@H](CCC5=C4)N6C7COCC6C7)=O)C

TAM Receptor

Axl

Room temperature