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AY77 [CAS 1835734-92-3]

AY77 [CAS 1835734-92-3]

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SKU:QM-0146498-01

£1,043.87 GBP
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  • Description

    AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release[1][2].

  • CAS Number

    [1835734-92-3]

  • Molecular Formula

    C21H32N4O4

  • Molecular Weight

    404.5

  • Smiles

    O=C(N)[C@H](C1CCCCC1)NC([C@H](CC2CCCCC2)NC(C3=CC=NO3)=O)=O

  • Target

    Protease Activated Receptor (PAR)

  • Isoform

    PAR2

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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AY77 [CAS 1835734-92-3]

AY77 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.