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SKU:QM-0151823-01
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AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively.
[915720-21-7]
C17H19ClFN7O
391.83
CC(OC1=CC(NC2=NC(N[C@H](C3=NC=C(F)C=C3)C)=NC=C2Cl)=NN1)C
Trk Receptor
TrkA; TrkB
98.92
DMSO : 125 mg/mL (ultrasonic)
-20°C, 3 years (Powder)
Blue Ice
H302, H315, H319, H335
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AZ-23 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.