AZD 2066 (hydrate)

AZD-2066 hydrate is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrate activates the BDNF/trkB signaling pathway. AZD 2066 hydrate can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease[1][2][3][5].

C19H16ClN5O2.1/4H2O

386.33

CN1C(C2=CC=NC=C2)=NN=C1O[C@@H](C3=NOC(C4=CC(Cl)=CC=C4)=C3)C.O.[1/4]

Calcium Channel; mGluR; Trk Receptor

MGluR5

99

10 mM in DMSO

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature