AZD5582 [CAS 1258392-53-8]

AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis[1].

[1258392-53-8]

C58H78N8O8

1015.29

CN[C@@H](C)C(N[C@H](C(N1[C@H](C(N[C@H]2C3=CC=CC=C3C[C@H]2OCC#CC#CCO[C@H]4[C@@H](NC([C@@H]5CCCN5C([C@@H](NC([C@H](C)NC)=O)C6CCCCC6)=O)=O)C(C=CC=C7)=C7C4)=O)CCC1)=O)C8CCCCC8)=O

Apoptosis; IAP

CIAP-1; cIAP-2; XIAP

99.61

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light, stored under nitrogen)

Room Temperature

H302

H302