AZD8233 sodium, a liver-targeting antisense oligonucleotide (ASO), inhibits subtilisin/kexin type 9 (PCSK9) protein synthesis. AZD8233 sodium increases the available LDL receptors by reducing PCSK9 levels, thereby clearing LDL from the blood and decreasing LDL-C levels.
Smiles
[AZD8233(sodium)]
Target
PCSK9
Purity
94.99
Solubility
10 mM in H2O
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)