AZD9362 [CAS 1905412-80-7]

AZD9362 is a reversible, ATP-competitive and orally active small molecule inhibitor of IGF-1R and insulin receptor. AZD9362 inhibits the IGF-1R enzyme with an IC50 of 14 nM. AZD9362 can enhance the anti-tumor effect of AZD5363. AZD9362 can be used for the research of cancer, such as breast cancer[1].

[1905412-80-7]

C24H27ClN8O2

494.98

CC1=NN(C2CCN(C([C@H](O)C)=O)CC2)C(C)=C1NC3=NC=C(Cl)C(C4=C5C=CC=CN5N=C4)=N3

IGF-1R; Insulin Receptor

Room temperature