Azide-PEG-azide (MW 20000)

Azide-PEG-azide (MW 20000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG-azide (MW 20000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

[N-]=[N+]=NCCOCCN=[N+]=[N-].[n].[MW20000]

PROTAC Linkers

PEG Linkers

10 mM in DMSO

Room temperature