Azido-PEG4-propargyl [CAS 1192590-91-2]

Azido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

[1192590-91-2]

C11H19N3O4

257.29

C#CCOCCOCCOCCOCCN=[N+]=[N-]

PROTAC Linkers

PEG Linkers

10 mM in DMSO

Room temperature

H301-H311-H331-H341

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501