Azido-PEG5-CH2CO2H [CAS 217180-81-9]

Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

[217180-81-9]

C12H23N3O7

321.33

O=C(O)COCCOCCOCCOCCOCCN=[N+]=[N-]

ADC Linker; PROTAC Linkers

Cleavable Linker; PEG Linkers

98.88

DMSO : 100 mg/mL (ultrasonic)

-20°C (Powder, protect from light)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335