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B-Raf IN 17
B-Raf IN 17
SKU:QM-0152444
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Product Details
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Description
B-Raf IN 17 (Compound 8e) is a potent and orally active type II multi-kinase inhibitor. B-Raf IN 17 exhibits potent cellular-level suppression of BRAFWT, VEGFR-2, and FGFR-1 in A375 cell line, with IC50 values of 0.02, 0.18 and 1.65 μM, respectively. B-Raf IN 17 can be used for the research of cancer[1].
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Molecular Formula
C22H14BrN5O2
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Molecular Weight
460.28
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Smiles
O=C(C1=CC=C2NC(C3=CC=CC=C3)=NC2=C1)N/N=C4C(NC5=C/4C=C(C=C5)Br)=O
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Target
FGFR; Raf; VEGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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B-Raf IN 17
B-Raf IN 17 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.