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B-Raf IN 5 [CAS 2648698-30-8]
B-Raf IN 5 [CAS 2648698-30-8]
SKU:QM-0065072
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Product Details
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Description
B-Raf IN 5 (compound 3b) is a potent inhibitor of protein kinase B-Raf with an IC50 of 2.0 nM. B-Raf IN 5 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].
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CAS Number
[2648698-30-8]
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Molecular Formula
C23H18ClF3N6O3S2
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Molecular Weight
583.01
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Smiles
O=S(C1=CC(F)=CC=C1F)(NC2=CC(Cl)=CC(C3=C(C4=NC(N)=NC=C4)SC(C5NCCOC5)=N3)=C2F)=O
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Target
Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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B-Raf IN 5 [CAS 2648698-30-8]
B-Raf IN 5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.