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B-Raf IN 7 [CAS 2477725-07-6]
B-Raf IN 7 [CAS 2477725-07-6]
SKU:QM-0067629
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Product Details
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Description
B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor, with an IC50 of 110.23 nM. B-Raf IN 7 exhibits antitumor activity against colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela) and human prostate cancer (PC-3) cells, with IC50 values of 7.50, 9.87, 10.57, 11.63 and 12.83 µM[1].
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CAS Number
[2477725-07-6]
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Molecular Formula
C15H16N6O3
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Molecular Weight
328.33
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Smiles
O=C(C1=C(N)N(C2=CC=C(C(CC3)=NNC3=O)C=C2)N=N1)OCC
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Target
Raf
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Isoform
B-Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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B-Raf IN 7 [CAS 2477725-07-6]
B-Raf IN 7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.