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B-Raf IN 8 [CAS 1215313-19-1]
B-Raf IN 8 [CAS 1215313-19-1]
SKU:QM-0067630
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Product Details
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Description
B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 µM[1].
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CAS Number
[1215313-19-1]
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Molecular Formula
C18H17N3O2
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Molecular Weight
307.35
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Smiles
O=C1CCC(C2=CC=C(/N=C/C3=CC=C(OC)C=C3)C=C2)=NN1
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Target
Raf
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Isoform
B-Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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B-Raf IN 8 [CAS 1215313-19-1]
B-Raf IN 8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.