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SKU:QM-0079129-01
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BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.
[1310347-50-2]
C18H14F3N5O2
389.33
O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)OCC3(F)F)=C2
Beta-secretase
BACE1
98.72
DMSO : 85 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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BACE1-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.