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BAY-293 [CAS 2244904-70-7]

BAY-293 [CAS 2244904-70-7]

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QM-0138421-01

£226.18 GBP
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Product Details

  • Description

    BAY-293, a valuable chemical probe, blocks RAS activation via disruption of the KRAS-SOS1 interaction with an IC50 of 21 nM. BAY-293 is a potent inhibitor of Son of Sevenless 1 (SOS1) . SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS[1].

  • CAS Number

    [2244904-70-7]

  • Molecular Formula

    C25H28N4O2S

  • Molecular Weight

    448.58

  • Smiles

    COC1=C(OC)C=C(N=C(C)N=C2N[C@H](C)C3=CC(C4=C(CNC)C=CC=C4)=CS3)C2=C1

  • Target

    Ras; SOS1

  • Isoform

    K-Ras

  • Purity

    98.97

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0138421-01
5 mgQM-0138421-01
£226.18/ea		 £0.00
£226.18/ea £0.00
10 mM - 1 mLQM-0138421-02
10 mM - 1 mLQM-0138421-02
£243.19/ea		 £0.00
£243.19/ea £0.00
10 mgQM-0138421-03
10 mgQM-0138421-03
£351.32/ea		 £0.00
£351.32/ea £0.00
25 mgQM-0138421-04
25 mgQM-0138421-04
£591.89/ea		 £0.00
£591.89/ea £0.00
50 mgQM-0138421-05
50 mgQM-0138421-05
£862.84/ea		 £0.00
£862.84/ea £0.00
100 mgQM-0138421-06
100 mgQM-0138421-06
£1,269.86/ea		 £0.00
£1,269.86/ea £0.00
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BAY-293 [CAS 2244904-70-7]

BAY-293 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.