BAY 36-7620 [CAS 232605-26-4]
BAY 36-7620 [CAS 232605-26-4]
SKU:QM-0057778
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Product Details
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Description
BAY 36-7620 is a potent and noncompetitive antagonist of mGlu1 Receptor (IC50=0.16 μM) with inverse agonist activity. BAY 36-7620 inhibits tumor growth and prolongs the survival of mice with tumors by inhibiting mGlu1 receptor. BAY 36-7620 suppresses AKT phosphorylation in A549 tumors. BAY 36-762 has neuroprotective effect in acute subdural hematoma rat model.BAY 36-7620 is used in non-small cell lung cancer and breast cancer research[1][2][3][4].
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CAS Number
[232605-26-4]
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Molecular Formula
C19H18O2
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Molecular Weight
278.35
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Smiles
C=C(C1)C[C@@](COC2=O)([H])[C@@]12CC3=CC4=C(C=CC=C4)C=C3
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Target
MGluR
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Isoform
MGluR1; mGluR2; mGluR5
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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BAY 36-7620 [CAS 232605-26-4]
BAY 36-7620 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.