BAZ1A-IN-1 [CAS 941521-45-5]

BAZ1A-IN-1 is a potent inhibitor of BAZ1A (bromodomain-containing protein) . BAZ1A-IN-1 shows a KD value of 0.52 μM against BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-viability activity against cancer cell lines expressing a high level of BAZ1A, but weak or no activity against cancer cells with a low expression level of BAZ1A[1].

[941521-45-5]

C16H12N4O3S

340.36

O=C(NC1=CC=CC([N+]([O-])=O)=C1)NC2=NC(C3=CC=CC=C3)=CS2

Epigenetic Reader Domain

99.91

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H315, H319

H302, H315, H319