BChE-IN-13 [CAS 2700896-73-5]

BChE-IN-13 (Compound 17c) is an orally active, potent and selective Butyrylcholinesterase (BChE) inhibitor with IC50s of 0.22 and 0.016 μM for eqBChE and hBChE, respectively. BChE-IN-13 can improve memory and cognitive impairments, and be used in Alzheimer’s disease (AD) research[1].

[2700896-73-5]

C24H28N2O

360.49

O=C(NC1=CC=CC=C1C)CN(CC(C)C)CC2=CC=C3C=CC=CC3=C2

Cholinesterase (ChE)

10 mM in DMSO

Room temperature