BChE-IN-30

BChE-IN-30 (compound (R) -37a) is a BChE inhibitor (IC50: 5 nM) with anti-inflammatory activity and low toxicity. BChE-IN-30 can improve cognitive deficits induced by scopolamine and Aβ1-42 peptide and can be used in the study of late-stage AD[1].

C23H39N3O3S

437.64

CC1=CC=C(C(N(CCC)CCC)=O)C=C1S(N[C@H](C)CN2CCCCCC2)(=O)=O

Cholinesterase (ChE)

10 mM in DMSO

Room temperature