BCL6 PROTAC 1 [CAS 2257479-54-0]

BCL6 PROTAC 1 is a selective B-cell lymphoma 6 (BCL6) PROTAC. BCL6 PROTAC 1 inhibits BCL6 cell reporter with an IC50 value of 8.8 µM. BCL6 PROTAC 1 significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines. BCL6 PROTAC 1 can be used in tumor related research[1].

[2257479-54-0]

C45H52ClN9O12

946.4

O=C(N1)C(N2C(C(C(OCCOCCOCCCNC(CCC(N3CCN(C4=NC=C(Cl)C(N5)=N4)[C@@H](COCCOC6=CC5=CC(CC7)=C6N(C)C7=O)C3)=O)=O)=CC=C8)=C8C2=O)=O)CCC1=O

BCL6; PROTACs

10 mM in DMSO

Room temperature