BCRP-IN-2 [CAS 2953730-35-1]

BCRP-IN-2 has BCRP inhibitory activity and shows even greater inhibition of BCRP after activation by ultraviolet light. BCRP-IN-2 can be a valuable probe for studying the interactions of quinazolinamine derivatives with BCRP, as it stimulates ATP hydrolysis of the BCRP transport protein, increasing the accumulation of mitoxantrone in H460/MX20 cells with BCRP overexpression[1].

[2953730-35-1]

C19H13N7

339.35

[N-]=[N+]=NC1=CC=C(NC2=NC(C3=CC=NC=C3)=NC4=CC=CC=C42)C=C1

BCRP

Room temperature