Belumosudil-d7

Belumosudil-d7 (KD025-d7) is deuterium labeled Belumosudil. Belumosudil (KD025) is a selective inhibitor of ROCK2 with IC50s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties[1].

C26H17D7N6O2

459.55

O=C(NC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])COC1=CC=CC(C2=NC(NC3=CC4=C(NN=C4)C=C3)=C5C=CC=CC5=N2)=C1

Isotope-Labeled Compounds; ROCK

Room temperature