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Belvarafenib [CAS 1446113-23-0]
Belvarafenib [CAS 1446113-23-0]
SKU:QM-0136394-01
£200.66 GBP
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Product Details
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Description
Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively[1].
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CAS Number
[1446113-23-0]
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Molecular Formula
C23H16ClFN6OS
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Molecular Weight
478.93
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Smiles
O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C
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Target
Raf
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Isoform
B-Raf; C-Raf
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Purity
98.97
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Solubility
DMSO : 12.5 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, stored under nitrogen)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Belvarafenib [CAS 1446113-23-0]
Belvarafenib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.