Bfl-1-IN-1

Bfl-1-IN-1 (Compound 15) is a potent and selective Bfl-1 inhibitor. Bfl-1-IN-1 inhibits Bfl-1 and Mcl-1 with Kis of 0.63 and 6.77 μM, respectively[1].

C31H31NO5S2

561.71

O=S(NC1=CC(SCC(O)=O)=C(OCC2CCCCC2)C3=CC=CC=C31)(C4=CC=C(C5=CC=CC=C5)C=C4)=O

Bcl-2 Family

10 mM in DMSO

Room temperature