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SKU:QM-0076586-01
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BGT226 (NVP-BGT226 maleate) is a PI3K (with IC50s of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ) /mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells[1][2].
[1245537-68-1]
C32H29F3N6O6
650.6
COC1=CC=C(C=N1)C2=CC=C(C3=C2)N=CC(N4C)=C3N(C4=O)C5=CC=C(C(C(F)(F)F)=C5)N6CCNCC6.OC(/C=C\C(O)=O)=O
Apoptosis; Autophagy; mTOR; PI3K
MTOR; PI3Kα; PI3Kβ; PI3Kγ
99.92
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)
4°C (Powder, sealed storage, away from moisture)
Room Temperature
H302, H315, H319, H335
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BGT226 (maleate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.