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SKU:QM-0079266-01
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BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair.
[300817-68-9]
C15H14BrNO3S2
400.31
O=C(O)C(C(C)C)N(C/1=O)C(SC1=C\C2=CC=C(Br)C=C2)=S
Bcl-2 Family; E1/E2/E3 Enzyme; MDM-2/p53
Bak; Bcl-2; Bcl-xL; Bim
98
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302+H312+H332
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BH3I-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.