BI 665915 [CAS 1360550-04-4]

BI 665915, a chemical probe, is an orally active and potent 5-lipoxygenase-activating protein (FLAP) inhibitor. BI 665915 inhibits FLAP production that blocks LTB4 biosynthesis in mice. BI 665915 is promising for research of various inflammatory diseases, including respiratory and cardiovascular diseases[1].

[1360550-04-4]

C24H26N8O2

458.52

C[C@@](C1CC1)(C2=CC=C(C3=CN=C(N)N=C3)C=C2)C4=NOC(C5=CN(N=C5)CC(N(C)C)=O)=N4

FLAP

Room temperature