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BI-749327 [CAS 2361241-23-6]

BI-749327 [CAS 2361241-23-6]

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QM-0137270-01

£257.76 GBP
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Product Details

  • Description

    BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7[1].

  • CAS Number

    [2361241-23-6]

  • Molecular Formula

    C23H21F3N4O2

  • Molecular Weight

    442.43

  • Smiles

    NC1=NN=C(C2CCN(C(C3=CC=C(OC4=CC=C(C(F)(F)F)C=C4)C=C3)=O)CC2)C=C1

  • Target

    TRP Channel

  • Purity

    99.91

  • Solubility

    DMSO : 31.25 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H315, H319, H335

  • Precautions

    H315, H319, H335
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Variant Variant total Quantity Price Variant total
1 mgQM-0137270-01
1 mgQM-0137270-01
£257.76/ea		 £0.00
£257.76/ea £0.00
5 mgQM-0137270-02
5 mgQM-0137270-02
£489.83/ea		 £0.00
£489.83/ea £0.00
10 mM - 1 mLQM-0137270-03
10 mM - 1 mLQM-0137270-03
£533.57/ea		 £0.00
£533.57/ea £0.00
10 mgQM-0137270-04
10 mgQM-0137270-04
£740.12/ea		 £0.00
£740.12/ea £0.00
50 mgQM-0137270-05
50 mgQM-0137270-05
£1,368.28/ea		 £0.00
£1,368.28/ea £0.00
100 mgQM-0137270-06
100 mgQM-0137270-06
£1,806.89/ea		 £0.00
£1,806.89/ea £0.00
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BI-749327 [CAS 2361241-23-6]

BI-749327 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.