Bim BH3, Peptide IV (TFA)

Bim BH3, Peptide IV TFA is a 26-residue peptide from BH3-only protein Bim, which belongs to the pro-apoptotic group of the Bcl-2 family of proteins[1][2].

C145H222N44O41S.xC2HF3O2

O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC([C@H](CCSC)NC([C@@H](N)CC(O)=O)=O)=O)=O)N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)CC2=CC=C(C=C2)O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O.OC(C(F)(F)F)=O

Bcl-2 Family

10 mM in DMSO

Room temperature