BIMAX2 (acetate)

BIMAX2 acetate is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 acetate can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 acetate can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence[1].

C146H254N64O41.xC2H4O2

CC(O)=O.O=C([C@@H](N)CCCNC(N)=N)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CCC2)=O)CCC1)=O)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CC3=CNC4=CC=CC=C34)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N.[x]

Ras

98.95

H2O : ≥ 100 mg/mL

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice