BIO8898

BIO8898 is a potent CD40-CD154 inhibitor. BIO8898 inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 μM. BIO8898 inhibits CD40L-induced apoptosis[1].

C53H64N8O6

909.13

O=C(O)[C@@H](NC(C1=NC(C(N2[C@H](CN3CCCC3)CCC2)=O)=CC(C4=CC(C(NCC5=CC(C6=CC=CC=C6)=CC=C5)=O)=NC(C(N7[C@H](CN8CCCC8)CCC7)=O)=C4)=C1)=O)C9CCCCC9

Apoptosis; TNF Receptor

TNFRSF5/CD40

10mM

99.88

DMSO : 50 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature