Biotin-TEG-ATFBA [CAS 1264662-85-2]

Biotin-TEG-ATFBA is a click chemistry reagent containing a perfluorophenylazide group. Biotin-TEG-ATFBA forms a highly stable azene intermediate that undergoes insertion and addition reactions (non-intermolecular rearrangement) in moderate to good yields after photolysis. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

[1264662-85-2]

C27H37F4N7O6S

663.68

O=C(C1=C(C(F)=C(C(F)=C1F)N=[N+]=[N-])F)NCCCOCCOCCOCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O

ADC Linker

99.09

10 mM in DMSO

-20°C, 3 years (Powder)

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