Biotin-YVAD-FMK

Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1[1][2].

C32H45FN6O9S

708.8

O=C([C@@H](NC(CCCC[C@@H]1SC[C@]([H])(N2)[C@@]1(NC2=O)[H])=O)CC3=CC=C(O)C=C3)N[C@H](C(N[C@H](C(N[C@H](C(CF)=O)CC(O)=O)=O)C)=O)C(C)C

Caspase

10 mM in DMSO

Room temperature