Biotinylated leptomycin B

Biotinylated leptomycin B is a compound used to quantify nuclear export protein 1 (XPO1) occupancy and is used to study the interaction of SINE compounds with XPO1 and the response of cancer cells to related compounds.

C49H76N4O7S

865.22

O=C(NCCCCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@H]3[C@@H](C)C=CC(O3)=O)=O

CRM1

99.32

DMSO : ≥ 300 mg/mL

-20°C (Powder, protect from light, stored under nitrogen)

Blue Ice