BLU0588 [CAS 2810747-78-3]

BLU0588 is an orally active, potent and selective PRKACA (protein kinase cAMP-activated catalytic subunit alpha) kinase inhibitor, with an IC50 of 1 nM and dissociation constant (Kd) of 4 nM. BLU0588 can be used for fibrolamellar carcinoma (FLC) research[1].

[2810747-78-3]

C26H25N5O

423.51

O=C(C1=CN=C(C2=C3C(NC=C3)=NC=C2)C=C1)N[C@H]4[C@H](N5CCCC5)CC6=CC=CC=C64

PKA

97.4

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years (Powder)

Blue Ice