BM-531 [CAS 284464-46-6]

BM-531 is a dual-acting agent for thromboxane receptor (TXA2) antagonism and thromboxane synthase inhibition. BM-531 exerts anti-aggregatory effects on human citrated platelet-rich plasma (PRP), inhibiting Arachidonic acid -induced aggregation with an ED100 of 0.125 μM and U-46619 (HY-108566) -induced aggregation with an ED50 of 0.482 μM. BM-531 inhibits high-K+-induced contraction of porcine uterine smooth muscle[1][2][3].

[284464-46-6]

C17H26N4O5S

398.48

O=S(C1=CC([N+]([O-])=O)=CC=C1NC2CCCCC2)(NC(NC(C)(C)C)=O)=O

Prostaglandin Receptor

10 mM in DMSO

Room temperature

H302-H315-H319-H335

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501