BMS-025

BMS-025 is a orthosteric STING agonist. BMS-025 can induces chemical shift of STING M271 residue, further activating STING IFN signaling. BMS-025 can be used for monogenic autoinflammatory disease like SAVI disease research[1].

C22H24N10O9P2S2

698.57

NC1=C2N=CN(C2=NC=N1)[C@@H]3C[C@@H]4OP(S)(OC[C@H]5O[C@H]([C@@H]([C@@H]5O)OP(S)(OC[C@H]43)=O)N6C=NC7=C6N=C8NC=CN8C7=O)=O

STING

Room temperature