BMS-354326 [CAS 708258-16-6]

BMS-354326 is a tryptase inhibitor with an IC50 of 1.8 nM. BMS-354326 exhibits excellent selectivity against trypsin and most other related serine proteases. BMS-354326 can be used in the research of asthma and inflammatory diseases[1].

[708258-16-6]

C28H40N4O5

512.64

O=C([C@H]([C@H]1CCC2CNCCC2)N(C(N3CCN(C(CCCCCC4=CC=CC=C4)=O)CC3)=O)C1=O)O

Ser/Thr Protease

Room temperature