BMS-986118 [CAS 1610562-74-7]

BMS-986118 is a potent, orally active, and selective GPR40 agonist with an EC50 of 0.07 µM. BMS-986118 has dual insulinotropic and GLP-1 secretory effects, resulting in robust plasma glucose lowering effects in acute animal models[1].

[1610562-74-7]

C25H28ClF3N4O4

540.96

COC1=CC(N2CC[C@H]([C@@H](C2)C)OC3=CC=C(C=C3)N4[C@H]([C@@H](C(C(F)(F)F)=N4)C)CC(O)=O)=C(C=N1)Cl

Free Fatty Acid Receptor

10 mM in DMSO

Room temperature