Name: BMS-986397 [CAS 2564486-44-6]
Brand: QuantiMol
SKU: QM-0152802-01
Price: 294.22 GBP
Availability: InStock

Product Details

Description
BMS-986397 is a cereblon-based CK1α (casein kinase 1α) molecular glue degrader that can cause rapid apoptosis and cell cycle arrest in TP53 wild-type AML (acute myeloid leukemia) cells. BMS-986397 can be used for the study of AML and HR-MDS (High-Risk Myelodysplastic Syndrome) [1].
CAS Number
[2564486-44-6]
Molecular Formula
C21H16ClF3N4O4
Molecular Weight
480.82
Smiles
O=C1CC[C@@H](C(N1)=O)N2CC3=C(C2=O)C=CC(C(N[C@@H](C(F)(F)F)C4=NC=CC=C4Cl)=O)=C3
Target
Apoptosis; Casein Kinase; Ligands for E3 Ligase; Molecular Glues
Isoform
Cereblon
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0152802-01	5 mgQM-0152802-01 £294.22/ea	£0.00	Quantity	£294.22/ea	£0.00

10 mgQM-0152802-02	10 mgQM-0152802-02 £432.73/ea	£0.00	Quantity	£432.73/ea	£0.00

25 mgQM-0152802-03	25 mgQM-0152802-03 £670.87/ea	£0.00	Quantity	£670.87/ea	£0.00

50 mgQM-0152802-04	50 mgQM-0152802-04 £916.29/ea	£0.00	Quantity	£916.29/ea	£0.00

100 mgQM-0152802-05	100 mgQM-0152802-05 £1,267.43/ea	£0.00	Quantity	£1,267.43/ea	£0.00

250 mgQM-0152802-06	250 mgQM-0152802-06 £1,882.22/ea	£0.00	Quantity	£1,882.22/ea	£0.00

500 mgQM-0152802-07	500 mgQM-0152802-07 £2,685.34/ea	£0.00	Quantity	£2,685.34/ea	£0.00

1 gQM-0152802-08	1 gQM-0152802-08 £3,753.32/ea	£0.00	Quantity	£3,753.32/ea	£0.00

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BMS-986397 [CAS 2564486-44-6]

BMS-986397 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.