BMS-986449

Name: BMS-986449
Brand: QuantiMol
SKU: QM-0011695-01
Price: 853.12 GBP
Availability: InStock

Size 5 mg 10 mg 25 mg 50 mg 100 mg

SKU:QM-0011695-01

£853.12 GBP

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Product Details

Description
BMS-986449 is a CELMoD molecular glue and an IKZF2/IKZF4 degrader. BMS-986449 targets the degradation of transcription factors Helios (IKZF2) and Eos (IKZF4) in regulatory T (Treg) cells. BMS-986449 redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos, reprogramming Treg cells and enhancing antitumor immunity. BMS-986449 is promising for research of advanced solid tumors[1].
Molecular Formula
C21H21FN4O3
Molecular Weight
396.41
Smiles
NC1=NC(C2=C(F)C([C@@H](C)N([C@H]3CCC(NC3=O)=O)C4=O)=C4C=C2)=CC(C)=C1C
Target
IKZF Family; Molecular Glues
Isoform
IKZF2; IKZF4
Shipping Conditions
Room temperature

Your cart
Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0011695-01	5 mgQM-0011695-01 £853.12/ea	£0.00	Quantity	£853.12/ea	£0.00

10 mgQM-0011695-02	10 mgQM-0011695-02 £1,330.61/ea	£0.00	Quantity	£1,330.61/ea	£0.00

25 mgQM-0011695-03	25 mgQM-0011695-03 £2,623.37/ea	£0.00	Quantity	£2,623.37/ea	£0.00

50 mgQM-0011695-04	50 mgQM-0011695-04 £4,191.94/ea	£0.00	Quantity	£4,191.94/ea	£0.00

100 mgQM-0011695-05	100 mgQM-0011695-05 £6,702.13/ea	£0.00	Quantity	£6,702.13/ea	£0.00

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BMS-986449 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.