BMT-124110 [CAS 1679371-59-5]

BMT-124110 is a potent, selective AAK1 inhibitor with an IC50 of 0.9 nM. BMT-124110 shows antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 17 and 99 nM, respectively[1].

[1679371-59-5]

C21H27N3O3

369.46

CC(NC1=CC2=C(COC3=CC(OC[C@@](C)(N)CC(C)C)=CC=C32)C=N1)=O

AAK1

99.15

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice