BO-1

BO-1 is a benzoate ester with antibacterial activity. BO-1 inhibits multidrug-resistant Staphylococcus aureus, and acts function synergistically with antibiotic, such as Ciprofloxacin. BO-1 can reverse the resistance of antibiotic-resistant S. aureus strains, and decreases the level of inflammatory factors IL-6 and C-reactive protein in vivo in mice[1].

C21H19ClO6

402.82

O[C@]1(COC(C2=CC=CC=C2)=O)[C@H](Cl)C=C[C@@H](OC(C3=CC=CC=C3)=O)[C@@H]1O

Bacterial

10 mM in DMSO

Room temperature