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BO-264 [CAS 2408648-20-2]

BO-264 [CAS 2408648-20-2]

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QM-0145305-01

£129.63 GBP
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Product Details

  • Description

    BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. BO-264 induces spindle assembly checkpoint (SAC) -dependent mitotic arrest, DNA damage and apoptosis. BO-264 has broad-spectrum antitumor activity[1].

  • CAS Number

    [2408648-20-2]

  • Molecular Formula

    C18H19N5O3

  • Molecular Weight

    353.38

  • Smiles

    COC1=CC=C(C2=NOC(NC3=NC(N4CCOCC4)=NC=C3)=C2)C=C1

  • Target

    Apoptosis; FGFR

  • Purity

    99.76

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0145305-01
5 mgQM-0145305-01
£129.63/ea		 £0.00
£129.63/ea £0.00
10 mM - 1 mLQM-0145305-02
10 mM - 1 mLQM-0145305-02
£139.75/ea		 £0.00
£139.75/ea £0.00
10 mgQM-0145305-03
10 mgQM-0145305-03
£238.32/ea		 £0.00
£238.32/ea £0.00
25 mgQM-0145305-04
25 mgQM-0145305-04
£351.32/ea		 £0.00
£351.32/ea £0.00
50 mgQM-0145305-05
50 mgQM-0145305-05
£501.98/ea		 £0.00
£501.98/ea £0.00
100 mgQM-0145305-06
100 mgQM-0145305-06
£727.97/ea		 £0.00
£727.97/ea £0.00
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BO-264 [CAS 2408648-20-2]

BO-264 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.